Strength-Duration curve is used to identify the status of a muscle as regards innervations, denervation or reinnervations can be indicated by these curves.
Nerve innervations and Denervations:
When the polarized membrane has a potential of -70 to -90 mV, Nerve action potential then eventually causes :
1. Ascending sensory impulses to the brain
2. Descending muscle action potential
Nerve repolarize quickly:- 0.4-2 msec (refractory period)
Diagnosis
- Foradic Galvanic test
- Measurement of rheobase and chronaxie
- Strength-Duration curve
- Nerve conduction velocity status
Faradic Galvanic Test
Faradic stimulus: No response in denervated muscles
Galvanic stimulus: Produces sluggish response
Measurements
Rheobase: Minimal current for the infinite duration (in practice 100 ms or more ) will cause contraction
Chronaixe: Minimal time for which a current of intensity twice rheobase will cause contraction
Both are increased in denervated nerves
Strength-Duration curve
Depending upon the excitability of the nerve and muscle a graph is prepared by plotting the minimal voltage required for the muscle to contract against the duration of the stimulus in milliseconds.
The Status of a muscle as regards innervations, denervation, or reinnervations can be indicated by these curves
Stimulation of the nerve requires a polarized membrane (Between inside and outside the nerve)
Strength – Duration Curve is a graph between electric stimuli of different intensities and recording the time needed by each stimulus to start the response.
SD curve is plotted after the 20th day of injury / Lesion
After 21st / 22nd day: 270 days to regenerate
The purpose of the SD curve is to know whether the stimulated muscle is innervated, denervated, or partially denervated.
Apparatus:
- Impulse with duration of 0.01, 0.03, 0.1, 0.3, 10, 30, 100, 300 ms are required.
- The stimulator may be of either the constant current or constant voltage type
- SD curve:- Representation of quantities nonlinear relationship between intensity and duration of current to determine whether the muscle is innervated or denervated.
Normal Innervation:
SD curve is of typical shape because the impulse of longer duration all produces a response with the same strength of the stimulus, irrespective of their duration, while those of shorter duration require an increase in strength of the stimulus each time the duration is reduced.
Complete Denervation:
The duration of impulse is 100ms or less, the strength of stimulus must be increased each time the duration is reduced and no response is obtained to impulse of short duration.
So, the curve rises steeply and is further to the right than normally innervated muscle.
Partial Denervation:
The impulse of longer duration can stimulate both innervated and denervated muscle fibers, so a contraction is obtained with a stimulus of low intensity
As impulses are shortened, the denervation fibers respond less readily, a shorter stimulus is required to produce a perceptible contraction and the curve rises steeply like denervated muscle
With the stimulus of shorter duration, the innervated fibers respond to a weaker stimulus than denervated fibers
The kink in SD Curve is seen at the point where 2 sectors meet
Kink appears in the curve and as reinnervated progress.
Advantages of SD Curves
- Simple, reliable, and cheaper
- Indicates proportion of denervation
- Less time consuming
Disadvantages of SD Curves
- Large fibers- Picture not clear
- Qualitative rather than the quantitative method
- It won’t point out the site of the lesion
See also: NanoTechnology in orthopedics
See also: Robotic Surgery in Orthopedics
See also: Properties of metals