Antibiotic resistance occurs due to overexposure to antibiotics in bacteria due to various causes.
![Antibiotic resistance](http://theorthonotes.com/storage/2022/05/image-15.png)
Penicillin attack the peptidoglycan which is resisted by the lipid layer in gram-negative bacterias: Cause of penicillin resistance in gram-negative organisms
![](http://theorthonotes.com/storage/2022/05/image-16.png)
Mechanisms of Antibiotic resistance
- Efflux
- Fluoroquinolones
- Aminoglycosides
- Tetracycline
- B-lactam
- Macrolides
- Immunity and Bypass
- Tetracycline
- Trimethoprim
- Sulfonamides
- Vancomycin
- Target modifications
- Fluoroquinolones
- Aminoglycosides
- Vancomycin
- Penicillin
- Macrolides
- Rifampicin
- Inactivating enzymes
- B-lactam
- Aminoglycosides
- Macrolides
- Rifampicin
See also: Acute Osteomyelitis
See also: General Principle of Infection